BDBM50434660 CHEMBL2387477

SMILES F[C@@H]1CNCC[C@@H]1CNc1ccn2ncc(C(=O)Nc3c[nH]c4ncccc34)c2n1

InChI Key InChIKey=CDQXYOYHHLAARJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50434660   

TargetSerine/threonine-protein kinase pim-1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50434660(CHEMBL2387477)
Affinity DataKi:  0.0570nMAssay Description:Inhibition of PIM1 (unknown origin) using FAM-pimtide as substrate after 90 mins by spectrophotometry in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50434660(CHEMBL2387477)
Affinity DataKi:  0.300nMAssay Description:Inhibition of PIM3 (unknown origin) using FAM-pimtide as substrate after 90 mins by spectrophotometry in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50434660(CHEMBL2387477)
Affinity DataKi:  21nMAssay Description:Inhibition of PIM2 (unknown origin) using FAM-pimtide as substrate after 90 mins by spectrophotometry in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed