BDBM50434842 CHEMBL2387509::US9040518, 13

SMILES CCCC[C@]1(CC)CS(=O)(=O)c2cc(CCC(=O)NCS(O)(=O)=O)c(OC)cc2[C@H](N1)c1ccccc1

InChI Key InChIKey=GHDJZKVROXOXFN-CLJLJLNGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434842   

TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50434842(CHEMBL2387509 | US9040518, 13)
Affinity DataIC50:  167nMAssay Description:Inhibition of human ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50434842(CHEMBL2387509 | US9040518, 13)
Affinity DataIC50:  167nMT: 2°CAssay Description:On the day of the uptake experiment, 10 mM HEPES was added to Hank's Balanced Salt Solution, and the pH was adjusted to 7.4 with TRIS (HBSSH). The as...More data for this Ligand-Target Pair
In DepthDetails US Patent