BDBM50435523 CHEMBL2392488

SMILES N#CCCN1CCC(CC1)n1nnc2cnc3[nH]ccc3c12

InChI Key InChIKey=BSDAVOOPCQRDNA-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50435523   

TargetTyrosine-protein kinase JAK1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435523(CHEMBL2392488)
Affinity DataKi:  2.10nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435523(CHEMBL2392488)
Affinity DataKi:  3.70nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435523(CHEMBL2392488)
Affinity DataEC50:  138nMAssay Description:Inhibition of JAK1-mediated STAT3 phosphorylation in IL6-induced human TF1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed