BDBM50436257 CHEMBL2398724

SMILES CC(C)[C@@H](NC(=O)[C@@H]1CCC[C@@H]1N)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1

InChI Key InChIKey=NNHDILPNEWHAFE-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50436257   

TargetC-C chemokine receptor type 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50436257(CHEMBL2398724)
Affinity DataIC50: 2.20nMAssay Description:Binding affinity to human CCR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50436257(CHEMBL2398724)
Affinity DataIC50: 5.60nMAssay Description:Antagonist activity at human CCR1 assessed as inhibition of MIP1alpha-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50436257(CHEMBL2398724)
Affinity DataEC50:  8.50E+3nMAssay Description:Induction of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed