BDBM50436258 CHEMBL2398722

SMILES CC(C)[C@@H](NC(=O)[C@@H]1CCC[C@@H]1O)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1

InChI Key InChIKey=BPFQMWZMSDPOCI-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50436258   

TargetC-C chemokine receptor type 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50436258(CHEMBL2398722)
Affinity DataIC50: 2.30nMAssay Description:Binding affinity to human CCR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50436258(CHEMBL2398722)
Affinity DataIC50: 3.10nMAssay Description:Antagonist activity at human CCR1 assessed as inhibition of MIP1alpha-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50436258(CHEMBL2398722)
Affinity DataEC50:  1.40E+3nMAssay Description:Induction of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed