BDBM50436959 CHEMBL2402257

SMILES CCOC(=O)c1cc(C#N)c(nc1C)N1CC(C1)NC(=O)NS(=O)(=O)c1ccccc1

InChI Key InChIKey=LROWHZKBLPBFIX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50436959   

TargetP2Y purinoceptor 12(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50436959(CHEMBL2402257)
Affinity DataIC50: 62nMAssay Description:Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50436959(CHEMBL2402257)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at P2Y12 receptor in human washed platelets assessed as inhibition of fibrinogen-induced aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50436959(CHEMBL2402257)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin) assessed as inhibition of GTPgammaS binding after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed