BDBM50437390 CHEMBL2408633

SMILES OC(=O)[C@H]1CC[C@@H](CC1)Oc1ccc(cn1)-c1ccc(cn1)-c1nc2ccc(Cl)cc2[nH]1

InChI Key InChIKey=AVNAVTDFGHCMQE-PPUGGXLSSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50437390   

LigandPNGBDBM50437390(CHEMBL2408633)
Affinity DataKi:  3.52E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50437390(CHEMBL2408633)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of human ACAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50437390(CHEMBL2408633)
Affinity DataIC50:  2nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50437390(CHEMBL2408633)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50437390(CHEMBL2408633)
Affinity DataIC50:  1.97E+3nMAssay Description:Inhibition of human ACAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50437390(CHEMBL2408633)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50437390(CHEMBL2408633)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed