BDBM50437847 CHEMBL2407893

SMILES Cc1ccc2c(c1)/C(=C\c1ccc3c(/C=C/c4ccncc4)n[nH]c3c1)C(=O)N2

InChI Key InChIKey=QDBKDMHYYVPUJY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50437847   

TargetSerine/threonine-protein kinase PLK4(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50437847BDBM50437847(CHEMBL2407893)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of N-terminal GST-tagged human PLK4 (1 to 391 amino acids) expressed in Escherichia coli using TMB as substrate after 30 mins by indirect ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50437847BDBM50437847(CHEMBL2407893)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PLK1 (unknown origin) by FRET-based homogeneous assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50437847BDBM50437847(CHEMBL2407893)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PLK3 (unknown origin) by FRET-based homogeneous assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50437847BDBM50437847(CHEMBL2407893)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PLK2 (unknown origin) by FRET-based homogeneous assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed