BDBM50438122 CHEMBL2409872

SMILES OC[C@H]1CCCCN1CCc1ccc(Nc2nc(cs2)-c2ccccc2F)cc1

InChI Key InChIKey=MAMJKOKHRZECFG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50438122   

TargetSphingosine kinase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50438122(CHEMBL2409872)
Affinity DataIC50: 120nMAssay Description:Inhibition of purified human SphK1 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSphingosine kinase 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50438122(CHEMBL2409872)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of purified human SphK2 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed