BDBM50438677 CHEMBL2414531

SMILES CCn1cc(cn1)-c1cccc2nc(Nc3ccnc(CO)c3)nn12

InChI Key InChIKey=IHOZCQOCOSYTJT-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50438677   

TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50438677(CHEMBL2414531)
Affinity DataKi:  3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50438677(CHEMBL2414531)
Affinity DataIC50: 115nMAssay Description:Inhibition of JAK2 in human SET2 cells assessed as reduction of phosphorylated STAT5 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed