BDBM50439267 CHEMBL2419475

SMILES CCCCc1cc2c(o1)c(N)nc1ccccc21

InChI Key InChIKey=TVEPYAGOSGVFCI-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50439267   

TargetToll-like receptor 8(Homo sapiens (Human))TBA

LigandBDBM50439267(CHEMBL2419475)Copy SMILESCopy InChI

Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at TLR8 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPDB

In DepthDetails PubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetToll-like receptor 8(Homo sapiens (Human))TBA

LigandBDBM50439267(CHEMBL2419475)Copy SMILESCopy InChI

Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells co-transfected with MD2 and sAP assessed as induction of NF-kappaB activity by reporter gene...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPDB

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI