BDBM50439335 CHEMBL2419760

SMILES C1Oc2cc3ncnc(Nc4cccc(c4)-c4ccccc4)c3cc2O1

InChI Key InChIKey=WYQRWWCPRIGMCS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50439335   

TargetEpidermal growth factor receptor(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50439335(CHEMBL2419760)
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFR (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50439335(CHEMBL2419760)
Affinity DataIC50: 32nMAssay Description:Inhibition of Src (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50439335(CHEMBL2419760)
Affinity DataIC50: 51nMAssay Description:Inhibition of Abl (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50439335(CHEMBL2419760)
Affinity DataIC50: 51nMAssay Description:Inhibition of Abl1 (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50439335(CHEMBL2419760)
Affinity DataIC50: 63nMAssay Description:Inhibition of FGFR1 (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50439335(CHEMBL2419760)
Affinity DataIC50: 243nMAssay Description:Inhibition of PDGFRbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed