BDBM50439469 CHEMBL2417696

SMILES CC(=S)NCCCC[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)OCc1ccccc1)C(=O)NCC(=O)c1ccccc1

InChI Key InChIKey=XYGZAKFJQKCMPT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50439469   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50439469(CHEMBL2417696)
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant GST-tagged SIRT1 using KI177 as substrate preincubated for 5 mins followed by enzyme addition measured after 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50439469(CHEMBL2417696)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 using KI179 as substrate preincubated for 5 mins followed by enzyme addition measured after 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50439469(CHEMBL2417696)
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of human recombinant His-tagged SIRT3 using KI179 as substrate preincubated for 5 mins followed by enzyme addition measured after 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed