BDBM50439514 CHEMBL2418352

SMILES CC(C)(O)c1nc2c(nc(nc2n1CCO)-c1cnc(N)nc1)N1CCOCC1

InChI Key InChIKey=FDDKQQRYIKXUCV-UHFFFAOYSA-N

Data  3 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50439514   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Genentech

Curated by ChEMBL

LigandBDBM50439514(CHEMBL2418352)Copy SMILESCopy InChI

Affinity DataKi:  2nMAssay Description:Displacement of TAMRA-PIP3 from PI3Kalpha GRP-1 pleckstrin homology domain (unknown origin) assessed as formation of 3,4,5-inositoltriphosphate after...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Genentech

Curated by ChEMBL

LigandBDBM50439514(CHEMBL2418352)Copy SMILESCopy InChI

Affinity DataKi:  4nMAssay Description:Displacement of TAMRA-PIP3 from PI3Kdelta GRP-1 pleckstrin homology domain (unknown origin) assessed as formation of 3,4,5-inositoltriphosphate after...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetSerine/threonine-protein kinase mTOR(Human)
Genentech

Curated by ChEMBL

LigandBDBM50439514(CHEMBL2418352)Copy SMILESCopy InChI

Affinity DataKi:  72nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL