BDBM50439720 CHEMBL2418955

SMILES CC(=O)Nc1cn2cc(ncc2n1)-c1cnc(N)c(c1)C(F)(F)F

InChI Key InChIKey=JVFYISFUURNKER-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50439720   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439720(CHEMBL2418955)
Affinity DataIC50: 110nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using [gamma33P]ATP as substrate by top counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed