BDBM50440022 CHEMBL2425787

SMILES COc1nc(NC(=O)[C@@H]2C[C@@]2(COc2cnc(C)nc2C)c2cccc(F)c2)ccc1F

InChI Key InChIKey=ZFEMHEFGCVEMHG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50440022   

TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50440022(CHEMBL2425787)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]-orexin-A from human OX2 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50440022(CHEMBL2425787)
Affinity DataKi:  12nMAssay Description:Displacement of [125I]-orexin-A from human OX1 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed