BDBM50440233 CHEMBL2426636

SMILES CCCC(c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(C)(C)C(=O)Nc1nncs1

InChI Key InChIKey=MATZYFFMBFOOKH-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50440233   

TargetGlucocorticoid receptor(Human)
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440233(CHEMBL2426636)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440233(CHEMBL2426636)
Affinity DataEC50:  18nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of PMA-induced AP-1 activation by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440233(CHEMBL2426636)
Affinity DataKi:  109nMAssay Description:Binding affinity to progesterone receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440233(CHEMBL2426636)
Affinity DataKi:  2.51E+3nMAssay Description:Binding affinity to androgen receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed