BDBM50440237 CHEMBL2426631

SMILES CC(C)(C(c1ccccc1)c1ccc2n(Cc3ccccc3)ncc2c1)C(=O)Nc1nncs1

InChI Key InChIKey=JJJXMWVSBHMOBI-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50440237   

TargetGlucocorticoid receptor(Human)
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440237(CHEMBL2426631)
Affinity DataKi:  14nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440237(CHEMBL2426631)
Affinity DataEC50:  1.93E+3nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of PMA-induced AP-1 activation by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed