BDBM50441510 CHEMBL2436621

SMILES Cc1nnc2CN(C3CCN(CC3)C(=O)C3(F)CCN(Cc4ccnc(N)c4)CC3)C(=O)c3ccsc3-n12

InChI Key InChIKey=CTGSDVZVJSPCBE-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50441510   

TargetHistamine H3 receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441510(CHEMBL2436621)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptor after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441510(CHEMBL2436621)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441510(CHEMBL2436621)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed