BDBM50442907 Acetyl Isogambogic Acid::CHEMBL3039433

SMILES CC(=O)Oc1c2c(c(CC=C(C)C)c3c1C(=O)C1=C[C@@H]4CC5C(C)(C)OC(C/C=C(\C)C(=O)O)(C4=O)[C@@]15O3)OC(C)(CCC=C(C)C)C=C2

InChI Key InChIKey=DKXTXNQAOLTATQ-UHFFFAOYSA-N

Data  2 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50442907   

LigandChemical structure of BindingDB Monomer ID 50442907BDBM50442907(CHEMBL3039433 | Acetyl Isogambogic Acid)
Affinity DataKi:  2.24E+3nMAssay Description:Ki values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50442907BDBM50442907(CHEMBL3039433 | Acetyl Isogambogic Acid)
Affinity DataIC50: 4.07E+3nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50442907BDBM50442907(CHEMBL3039433 | Acetyl Isogambogic Acid)
Affinity DataKi:  4.17E+3nMAssay Description:Ki values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50442907BDBM50442907(CHEMBL3039433 | Acetyl Isogambogic Acid)
Affinity DataIC50: 5.37E+3nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
University of Delaware

LigandChemical structure of BindingDB Monomer ID 50442907BDBM50442907(CHEMBL3039433 | Acetyl Isogambogic Acid)
Affinity DataIC50: 5.40E+3nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 15(Human)
University of Delaware

LigandChemical structure of BindingDB Monomer ID 50442907BDBM50442907(CHEMBL3039433 | Acetyl Isogambogic Acid)
Affinity DataIC50: 1.11E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Human)
University of Delaware

LigandChemical structure of BindingDB Monomer ID 50442907BDBM50442907(CHEMBL3039433 | Acetyl Isogambogic Acid)
Affinity DataIC50: 1.54E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
University of Delaware

LigandChemical structure of BindingDB Monomer ID 50442907BDBM50442907(CHEMBL3039433 | Acetyl Isogambogic Acid)
Affinity DataIC50: 1.82E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L5(Human)
University of Delaware

LigandChemical structure of BindingDB Monomer ID 50442907BDBM50442907(CHEMBL3039433 | Acetyl Isogambogic Acid)
Affinity DataIC50: 3.65E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed