BDBM50443754 CHEMBL3093905

SMILES COc1ccc(C[C@H](N)C(=O)N2C[C@@H](F)C[C@H]2C#N)cc1

InChI Key InChIKey=YIYAUIWJPDJXEC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50443754   

TargetDipeptidyl peptidase 4(Human)
Pcte Group of Institutes

Curated by ChEMBL
LigandPNGBDBM50443754(CHEMBL3093905)
Affinity DataIC50: 5nMAssay Description:Inhibition of DPP-4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50443754(CHEMBL3093905)
Affinity DataIC50: 140nMAssay Description:Inhibition of 6xHis-tagged recombinant FAP (unknown origin) expressed in baculovirus expression system assessed as hydrolysis of Nle-Pro-aminomethylc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50443754(CHEMBL3093905)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant DPP8 (unknown origin) expressed in baculovirus expression system assessed as hydrolysis of Ala-Pro-aminomethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50443754(CHEMBL3093905)
Affinity DataIC50: 2.87E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant DPP9 (unknown origin) expressed in baculovirus expression system assessed as hydrolysis of Ala-Pro-aminomethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed