BDBM50446145 CHEMBL3108910

SMILES CN(CC(=O)N(Cc1ccc(cc1)C1CCCCC1)c1ccc(cc1)C(=O)NO)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F

InChI Key InChIKey=QPSUYVALAOXFGL-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50446145   

TargetSignal transducer and activator of transcription 3(Mouse)
University of Hawaii Cancer Center

Curated by ChEMBL
LigandPNGBDBM50446145(CHEMBL3108910)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of STAT3 DNA binding activity in mouse NIH/3T3 nuclear extract preincubated for 30 mins followed by [32P]hSIE addition measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Zhejiang Chinese Medical University

Curated by ChEMBL
LigandPNGBDBM50446145(CHEMBL3108910)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of STAT3 (unknown origin) binding to DNA by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Zhejiang Chinese Medical University

Curated by ChEMBL
LigandPNGBDBM50446145(CHEMBL3108910)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of STAT3 (unknown origin) DNA binding activity by EMSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Zhejiang Chinese Medical University

Curated by ChEMBL
LigandPNGBDBM50446145(CHEMBL3108910)
Affinity DataKi:  1.00E+4nMAssay Description:Competitive binding affinity to STAT3 SH2 domain (unknown origin) assessed as inhibition of interaction with FAMpYLPQTV after 15 to 30 mins by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed