BDBM50446470 CHEMBL3109985::US9765054, Compound 46

SMILES ONC(=O)[C@@H]1[C@@H]([C@H]1c1ccc(cc1)-c1cnc(o1)C1CC1)c1ccccc1

InChI Key InChIKey=VFVVXZLMBWETAN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50446470   

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM50446470(CHEMBL3109985 | US9765054, Compound 46)
Affinity DataIC50: 40nMAssay Description:5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446470(CHEMBL3109985 | US9765054, Compound 46)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446470(CHEMBL3109985 | US9765054, Compound 46)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446470(CHEMBL3109985 | US9765054, Compound 46)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed