BDBM50446474 CHEMBL3109980::US9765054, Compound 25e

SMILES ONC(=O)[C@@H]1[C@@H]([C@H]1c1cc(Cl)c2OCCOc2c1)c1ccccc1

InChI Key InChIKey=MMWFLIBCIOFXBI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446474   

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM50446474(CHEMBL3109980 | US9765054, Compound 25e)
Affinity DataIC50: 20nMAssay Description:5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446474(CHEMBL3109980 | US9765054, Compound 25e)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human recombinant full length HDAC3-NCoR2 using Lys_Ac_AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed