BDBM50446754 CHEMBL3114609

SMILES OC(=O)c1ccc(OC2CCN(CC2)C(=O)N[C@H]2C[C@@H]2c2ccccc2)c(Cl)c1

InChI Key InChIKey=VYIHTZCGBYAQRV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50446754   

TargetBifunctional epoxide hydrolase 2(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50446754(CHEMBL3114609)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50446754(CHEMBL3114609)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50446754(CHEMBL3114609)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50446754(CHEMBL3114609)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed