BDBM50447200 CHEMBL3113195::US10752581, Compound 65

SMILES COc1cccc(CNc2ccc(cc2)S(=O)(=O)Nc2cccc(c2)C2CCN(CC2)C(=O)OC(C)(C)C)c1O

InChI Key InChIKey=JRVFMYCYGBPQMM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50447200   

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
Eastern Virginia Medical School

US Patent
LigandPNGBDBM50447200(CHEMBL3113195 | US10752581, Compound 65)
Affinity DataIC50: 760nMAssay Description:UV-vis cuvette-based assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
Eastern Virginia Medical School

US Patent
LigandPNGBDBM50447200(CHEMBL3113195 | US10752581, Compound 65)
Affinity DataIC50: 760nMAssay Description:Inhibition of N-terminal His6-tagged human platelet 12-LOX using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed