BDBM50448100 CHEMBL3121330

SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1cnc2nc(N)c(cc2c1)-c1ccccc1

InChI Key InChIKey=SBYFOHJJQOLDEW-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448100   

TargetPhosphatidylinositol 4-kinase alpha(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50448100(CHEMBL3121330)Copy SMILESCopy InChI

Affinity DataIC50: 631nMAssay Description:Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/26/2014
Entry Details Article
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50448100(CHEMBL3121330)Copy SMILESCopy InChI

Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/26/2014
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL