BDBM50448123 CHEMBL3122108::US9212186, 16

SMILES CNc1nc(Nc2cnn3CCOC(C)c23)ncc1C(F)(F)F

InChI Key InChIKey=YCUKUBANXXIFKX-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50448123   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50448123(CHEMBL3122108 | US9212186, 16)
Affinity DataKi:  3nMAssay Description:This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50448123(CHEMBL3122108 | US9212186, 16)
Affinity DataKi:  3nMAssay Description:Inhibition of LRRK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50448123(CHEMBL3122108 | US9212186, 16)
Affinity DataKi:  279nMAssay Description:This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50448123(CHEMBL3122108 | US9212186, 16)
Affinity DataIC50:  42nMAssay Description:Inhibition of LRRK2 (unknown origin) phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed