BDBM50448644 CHEMBL3127513::US10696692, Example 149
SMILES O=C(NCc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C1COC1)c1cc2ccncc2o1
InChI Key InChIKey=OGDYOHGOSNSDAE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50448644
Affinity DataIC50: 28nMAssay Description:Inhibition of C-terminal His-tagged human full-length NAMPT expressed in Escherichia coli Rosetta DE3 using nicotinamide as substrate preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 28.3nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Affinity DataKd: 80nMAssay Description:Binding affinity to NAMPT (2 to 491) (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair