BDBM50449473 CHEMBL4165503::US20250163056, Compound BPN-0026544

SMILES Cc1ccc2N=C3N(CC[C@@]3(O)C(=O)c2c1)c1ccc(Cl)cc1

InChI Key InChIKey=DHAADFMSKONJNO-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50449473   

TargetMyosin-2 heavy chain(Social amoeba)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50449473BDBM50449473(CHEMBL4165503 | US20250163056, Compound BPN-002654...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Dictyostelium discoideum myosin 2 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMyosin-2(Human)
University of Florida Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50449473BDBM50449473(CHEMBL4165503 | US20250163056, Compound BPN-002654...)
Affinity DataKi:  4.80E+3nMAssay Description:The skeletal muscle myosin II actin-activated ATPase assay is performed the same as for cardiac muscle myosin II with the following exceptions: Rabbi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent