BDBM50451735 CHEMBL4207499

SMILES OC(=O)Cn1c2CCN(Cc2c2cc(F)ccc12)C(=O)c1ccc2ccccc2c1

InChI Key InChIKey=OSPYHSMJASUWOU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50451735   

TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451735(CHEMBL4207499)
Affinity DataIC50:  141nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451735(CHEMBL4207499)
Affinity DataIC50:  141nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451735(CHEMBL4207499)
Affinity DataIC50:  4.38E+4nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed