BDBM50451874 CHEMBL4202591

SMILES Fc1cccc(N(C(=O)[C@@H]2CCC(=O)N2c2cc(ccn2)C#N)[C@]2(CCc3ccccc23)C(=O)NC2CC(F)(F)C2)c1F

InChI Key InChIKey=MVWXGLHAVGYHTP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50451874   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe

Curated by ChEMBL
LigandPNGBDBM50451874(CHEMBL4202591)
Affinity DataIC50: 148nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed