BDBM50453439 CHEMBL4209440

SMILES COC(=O)Cc1ccc(OCc2oc(nc2C)-c2cccc(OC)c2)cc1

InChI Key InChIKey=GFUKCIXVOZBJQK-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50453439   

TargetVitamin D3 receptor(Human)TBA
LigandChemical structure of BindingDB Monomer ID 50453439BDBM50453439(CHEMBL4209440)
Affinity DataIC50: 660nMAssay Description:Antagonist activity at CMV-fused VDR (unknown origin) expressed in HEK293T cells assessed as reduction in 24-hydroxylase promoter mediated transcript...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50453439BDBM50453439(CHEMBL4209440)
Affinity DataIC50: 970nMAssay Description:Antagonist activity at CMV-fused TRbeta-LBD-GAL4-DBD (unknown origin) expressed in HEK293T cells assessed as inhibition of T3-induced receptor transa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)TBA
LigandChemical structure of BindingDB Monomer ID 50453439BDBM50453439(CHEMBL4209440)
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at CMV-fused ERalpha-LBD-GAL4-DBD (unknown origin) expressed in HEK293T cells assessed as inhibition of estradiol-induced recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50453439BDBM50453439(CHEMBL4209440)
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at CMV-fused PPARalpha-LBD-GAL4-DBD (unknown origin) expressed in HEK293T cells assessed as inhibition of GW7647-induced receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50453439BDBM50453439(CHEMBL4209440)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at CMV-fused RXRalpha-LBD-GAL4-DBD (unknown origin) expressed in HEK293T cells assessed as inhibition of bexarotene-induced recep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50453439BDBM50453439(CHEMBL4209440)
Affinity DataIC50: 4.20E+3nMAssay Description:Antagonist activity at CMV-fused TRalpha-LBD-GAL4-DBD (unknown origin) expressed in HEK293T cells assessed as inhibition of T3-induced receptor trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50453439BDBM50453439(CHEMBL4209440)
Affinity DataIC50: 6.70E+3nMAssay Description:Antagonist activity at CMV-fused PPARgamma-LBD-GAL4-DBD (unknown origin) expressed in HEK293T cells assessed as inhibition of rosiglitazone-induced r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)TBA
LigandChemical structure of BindingDB Monomer ID 50453439BDBM50453439(CHEMBL4209440)
Affinity DataIC50: 7.40E+3nMAssay Description:Antagonist activity at CMV-fused ERbeta-LBD-GAL4-DBD (unknown origin) expressed in HEK293T cells assessed as inhibition of estradiol-induced receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50453439BDBM50453439(CHEMBL4209440)
Affinity DataIC50: 1.13E+4nMAssay Description:Antagonist activity at CMV-fused PPARdelta-LBD-GAL4-DBD (unknown origin) expressed in HEK293T cells assessed as inhibition of GW0742-induced receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)TBA
LigandChemical structure of BindingDB Monomer ID 50453439BDBM50453439(CHEMBL4209440)
Affinity DataIC50: 1.39E+4nMAssay Description:Antagonist activity at VP16-fused VDR-LBD (unknown origin) expressed in HEK293T cells assessed as inhibition of ligand-induced GAL4-fused SRC1 coacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed