BDBM50453461 CHEMBL4213767

SMILES CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1c(N)c2sccc2[nH]c1=O

InChI Key InChIKey=QVLFEWNYZXVCHO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50453461   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50453461(CHEMBL4213767)
Affinity DataIC50: 50nMAssay Description:Inhibition of HPK1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50453461(CHEMBL4213767)
Affinity DataIC50: 50nMAssay Description:Inhibition of FLT3 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50453461(CHEMBL4213767)
Affinity DataIC50: 50nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50453461(CHEMBL4213767)
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal GST-tagged human HPK1 (1 to 346 residues) after 30 mins in presence of ATP by indirect ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed