BDBM50453964 CHEMBL4213692::US11247989, Example 80

SMILES CCc1cncc2c(cccc12)-c1nn(C2CCOCC2)c2CCN(Cc12)C(C)=O

InChI Key InChIKey=IIKPEYATRJQMQZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50453964   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandPNGBDBM50453964(CHEMBL4213692 | US11247989, Example 80)
Affinity DataIC50: 37.8nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandPNGBDBM50453964(CHEMBL4213692 | US11247989, Example 80)
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant His-tagged CBP (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50453964(CHEMBL4213692 | US11247989, Example 80)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed