BDBM50453974 CHEMBL4203862::US11247989, Example 4

SMILES CC(=O)N1CCc2c(C1)c(nn2C1CCOCC1)-c1cc(C)cc2ccncc12

InChI Key InChIKey=AXZGDIGHFALXJO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50453974   

TargetCREB-binding protein(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50453974(CHEMBL4203862 | US11247989, Example 4)
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant His-tagged CBP (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50453974(CHEMBL4203862 | US11247989, Example 4)
Affinity DataIC50: 58.1nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50453974(CHEMBL4203862 | US11247989, Example 4)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed