BDBM50454419 CHEMBL5283875

SMILES COc1cc2ncnc(Nc3ccccc3NC(=O)C=C)c2cc1OCCN1CCOCC1

InChI Key InChIKey=NEWANAUWTDNRAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50454419   

TargetEpidermal growth factor receptor(Human)
School of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50454419(CHEMBL5283875)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of EGFR L858R/T790M (unknown origin) incubated for 60 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
School of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50454419(CHEMBL5283875)
Affinity DataIC50: 24nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 60 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed