BDBM50455470 CHEMBL4213046

SMILES COc1cccc(Cn2c(SCC(=O)Nc3nc4ccc(cc4s3)C(F)(F)F)nc3CCSc3c2=O)c1OC

InChI Key InChIKey=ASNBCMDJKIZLOU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50455470   

TargetCasein kinase I isoform delta(Rat)
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455470(CHEMBL4213046)
Affinity DataIC50:  230nMAssay Description:Inhibition of rat recombinant CK1delta kinase domain using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rat)
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455470(CHEMBL4213046)
Affinity DataIC50:  760nMAssay Description:Inhibition of full-length rat GST-tagged CK1delta using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Human)
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455470(CHEMBL4213046)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of human recombinant CK1epsilon using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rat)
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50455470(CHEMBL4213046)
Affinity DataIC50:  210nMAssay Description:Inhibition of rat GST-tagged CK1delta M82F mutant at 10 uM using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed