BDBM50456190 CHEMBL4205190

SMILES OC(=O)c1cc(O)c2ccc(cc2c1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=KXCZWPBLAFRHPX-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50456190   

TargetP2Y purinoceptor 14(Mouse)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50456190(CHEMBL4205190)
Affinity DataIC50: 1.60E+3nMAssay Description:Displacement of Alexafluor488 labeled 4-(4-(1-(4-(1-(6-(4-(6-amino-3-imino-4,5-disulfo-3H-xanthen-9-yl)-3-carboxybenzamido)hexyl)-1H-1,2,3-triazol-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetP2Y purinoceptor 14(Human)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50456190(CHEMBL4205190)
Affinity DataIC50: 3.20E+3nMAssay Description:Displacement of Alexafluor488 labeled 4-(4-(1-(4-(1-(6-(4-(6-amino-3-imino-4,5-disulfo-3H-xanthen-9-yl)-3-carboxybenzamido)hexyl)-1H-1,2,3-triazol-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetP2Y purinoceptor 14(Human)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50456190(CHEMBL4205190)
Affinity DataIC50: 3.20E+3nMAssay Description:Displacement of MRS4174 from human P2Y14R expressed in CHO cells preincubated for 30 mins followed by MRS4174 addition measured after 30 mins by flow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50456190(CHEMBL4205190)
Affinity DataKi:  5.80E+3nMAssay Description:Displacement of [3H]-Nisoxetine from human NET expressed in HEK293 cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed