BDBM50456711 CHEMBL4208641

SMILES C(CCNc1c2CCCCc2nc2ccccc12)CCSSCCCCCNc1c2CCCCc2nc2ccccc12

InChI Key InChIKey=CSHQXRFENGZQAM-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50456711   

TargetAcetylcholinesterase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50456711(CHEMBL4208641)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50456711(CHEMBL4208641)
Affinity DataKi:  3.10nMAssay Description:Mixed-type inhibition of electric eel AChE assessed as enzyme-inhibitor complex using p-nitrophenyl acetate as substrate by Lineweaver-Burk plot anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50456711(CHEMBL4208641)
Affinity DataKi:  5.70nMAssay Description:Mixed-type inhibition of electric eel AChE assessed as enzyme-substrate-inhibitor complex using p-nitrophenyl acetate as substrate by Lineweaver-Burk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50456711(CHEMBL4208641)
Affinity DataKi:  166nMAssay Description:Mixed-type inhibition of equine serum BuChE assessed as enzyme-inhibitor complex using p-nitrophenyl butyrate as substrate by Lineweaver-Burk plot an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50456711(CHEMBL4208641)
Affinity DataKi:  422nMAssay Description:Mixed-type inhibition of equine serum BuChE assessed as enzyme-substrate-inhibitor complex using p-nitrophenyl butyrate as substrate by Lineweaver-Bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed