BDBM50457202 CHEMBL4207969

SMILES COc1ccc(cc1OC)C(=O)n1nc(nc1N)-c1cccnc1

InChI Key InChIKey=TXTSSGLLPOYFAL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50457202   

TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457202(CHEMBL4207969)
Affinity DataIC50: 160nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457202(CHEMBL4207969)
Affinity DataIC50: 190nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457202(CHEMBL4207969)
Affinity DataIC50: 970nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.01% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457202(CHEMBL4207969)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.02% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstate-specific antigen(Human)
University of Missouri - Columbia

Curated by ChEMBL
LigandPNGBDBM50457202(CHEMBL4207969)
Affinity DataKi:  1.38E+4nMAssay Description:Inhibition of recombinant human semen PSA using Mu-HSSKLQAMC as substrate preincubated for 15 mins followed by substrate addition by fluorescence bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed