BDBM50457869 CHEMBL4217096
SMILES COc1ccc(NC(=O)N2CCN(CC2)c2nc(N)nc3scnc23)cc1
InChI Key InChIKey=PFSGRYSHTMXMAJ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50457869
Affinity DataIC50: 53nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as decrease in midazolam 1-hydroxylation by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ucb Pharma
Curated by ChEMBL
Ucb Pharma
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human ERG by cell based automated patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair