BDBM50458314 CHEMBL4217579
SMILES CCc1ccc(o1)[C@H]1N(Cc2c1[nH]c1ccccc1c2=O)c1ncc(cn1)-c1ccccn1
InChI Key InChIKey=RNHNQORGLGCJLQ-XMMPIXPASA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50458314
Affinity DataIC50: 0.390nMAssay Description:Inhibition of human DNA polymerase delta using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 minsMore data for this Ligand-Target Pair
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 5.10nMAssay Description:Inhibition of N-terminal GST-tagged full length recombinant human PDE11A expressed in Baculovirus infected Sf9 insect cells using FAM-cAMP as substra...More data for this Ligand-Target Pair
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Human)
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of N-terminal GST-tagged full length recombinant human PDE6C expressed in Baculovirus infected Sf9 insect cells using FAM-cAMP as substrat...More data for this Ligand-Target Pair