BDBM50458534 CHEMBL4216226

SMILES Oc1cc(=O)[nH]c2ccc(cc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCc1cc(=O)[nH]c2ccc(Cl)cc12

InChI Key InChIKey=DNDMLXSODUEUMP-DEOSSOPVSA-N

Data  1 KI  1 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50458534   

TargetCoagulation factor XI(Homo sapiens (Human))
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50458534(CHEMBL4216226)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human factor 11a using pyroGlu-Pro-Arg-pNA.HCl as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCoagulation factor XI(Homo sapiens (Human))
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50458534(CHEMBL4216226)
Affinity DataIC50:  1nMAssay Description:Inhibition of human factor 11a assessed as reduction in para-nitroanilide releasee using pyroGlu-Pro-Arg-pNA.HCl substrate by by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB