BDBM50458669 CHEMBL4215049

SMILES [H][C@@]12CC[C@]1([H])N(C(=O)c1cccc(OC(F)(F)F)c1)c1ccccc1[C@@H]2N(C1CC1)C(=O)CCC(O)=O

InChI Key InChIKey=IMGYHBFOPYFDNC-IZIIKQMZSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50458669   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458669(CHEMBL4215049)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458669(CHEMBL4215049)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at CRTh2 in human whole blood assessed as inhibition of DK-PGD2-induced eosinophils shape change preincubated for 10 mins followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458669(CHEMBL4215049)
Affinity DataIC50:  43nMAssay Description:Antagonist activity at human CRTh2 expressed in CHOK1 cells assessed as inhibition of PGD2-induced beta-arrestin recruitment incubated for 30 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed