BDBM50459095 CHEMBL4210783

SMILES OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(=O)NCCCN(CCCNC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)C(=O)NCCCCOc1cc(Cl)c(CN2CSC[C@H]2C(=O)N2CCN(C3CC3)c3ccccc23)cc1Cl

InChI Key InChIKey=MWROCFGTUYEBMJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50459095   

TargetG-protein coupled bile acid receptor 1(Mouse)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50459095(CHEMBL4210783)
Affinity DataEC50:  40nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed