BDBM50459159 CHEMBL4204919

SMILES OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](NC(=O)CCCCc1cc(Cl)c(CN2CSC[C@H]2C(=O)N2CCN(C3CC3)c3ccccc23)cc1Cl)C(O)=O

InChI Key InChIKey=MAPQRVHQTODEMD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50459159   

TargetG-protein coupled bile acid receptor 1(Mouse)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50459159(CHEMBL4204919)
Affinity DataEC50:  4nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed