BDBM50459674 CHEMBL4218959::US12006283, Example 9

SMILES COc1ccc(cc1OC)C(C)C(=O)c1ccc(NCc2ccccc2)cc1OC

InChI Key InChIKey=RAHBTVBFKALZFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50459674   

TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

US Patent
LigandPNGBDBM50459674(CHEMBL4218959 | US12006283, Example 9)
Affinity DataIC50: 1.43E+3nMAssay Description:The experiment was performed in order to evaluate inhibitory activity against angiogenesis of the compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2024
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

US Patent
LigandPNGBDBM50459674(CHEMBL4218959 | US12006283, Example 9)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed