BDBM50459720 CHEMBL4210305

SMILES COc1ccc(CN(CCN(C)C)c2ccc(cn2)C(=O)Nc2ccccc2N)cc1

InChI Key InChIKey=XRDCTVBYPFNFSI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50459720   

TargetHistone deacetylase 1(Human)
Kansai University

Curated by ChEMBL
LigandPNGBDBM50459720(CHEMBL4210305)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using HDAC substrate 3 measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Kansai University

Curated by ChEMBL
LigandPNGBDBM50459720(CHEMBL4210305)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of recombinant human C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using HDAC substrate 3 measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandPNGBDBM50459720(CHEMBL4210305)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human full length C-terminal His-tagged HDAC3/N-terminal GST-tagged human NCOR2 (395 to 489 residues) co-expressed in baculovirus infec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Kansai University

Curated by ChEMBL
LigandPNGBDBM50459720(CHEMBL4210305)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of human HDAC10 expressed in baculovirus infected Sf9 insect cells using HDAC substrate 3 measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed