BDBM50459927 CHEMBL4227573

SMILES C1C2CNC[C@]12c1ccc2ccccc2c1

InChI Key InChIKey=HKHCSWPSUSWGLI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50459927   

TargetSodium-dependent noradrenaline transporter(Human)
Biocon Bristol-Myers Squibb R&D Centre

Curated by ChEMBL
LigandPNGBDBM50459927(CHEMBL4227573)
Affinity DataIC50: 6nMAssay Description:Inhibition of human NET expressed in HEK cells assessed as reduction of [3H]-NE uptake preincubated for 10 mins followed by [3H]5-HT addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Biocon Bristol-Myers Squibb R&D Centre

Curated by ChEMBL
LigandPNGBDBM50459927(CHEMBL4227573)
Affinity DataIC50: 38nMAssay Description:Inhibition of human DAT expressed in HEK cells assessed as reduction of [3H]-DA uptake preincubated for 10 mins followed by [3H]5-HT addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Biocon Bristol-Myers Squibb R&D Centre

Curated by ChEMBL
LigandPNGBDBM50459927(CHEMBL4227573)
Affinity DataIC50: 84nMAssay Description:Inhibition of human SERT expressed in HEK cells assessed as reduction of [3H]5-HT uptake preincubated for 10 mins followed by [3H]5-HT addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed